Sites and web services that you use constantly are better taken out of the browser and made individual processes on your desktop. This means that when you close the browser, or if it crashes, the sites you’re running individually (prosper202 for example) will not be affected. This is a major problem because nowadays we do most of our work in the browser.
Google Chrome solves this problem by making each tab/window an individual process. The problem with Google Chrome is that there really is no need to have the entire browser running just to view 1 site, which may be static. Instead, look into some of the apps created specifically for this task. These are termed Site-Specific-Browsers (SSB)s, and they’ve existed for a few years now.
There are alternatives but I use Mozilla Prism (or any of the alternatives). Prism is basically a minimal browser which is intended to display one site only (per instance of Prism). It also creates a desktop/start menu icon to quickly open that specific site/web app.
An excellent example of a web service that should be run off the browser is Google Calendar. I have this turned on full screen 24/7 on one of my desktops. I can restart Firefox every time it begins exhibiting its annoying memory leak feature, and the calendar will remain open and fast. Some other great services to keep running are your prosper202/tracking202 accounts, PPC accounts, SplitTester.com, and maybe some forums you frequent often.